Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 16/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362029 | 0.79 | KMT2A (0.65) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL27906644 | 0.77 | KMT2A (0.63) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL16797440 | 0.76 | KMT2A (0.74) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL26490187 | 0.76 | SLC6A3 (0.72) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL6340252 | 0.76 | KMT2A (0.61) | KMT2AALDH1A1MAPTMEN1CYP1A2 | |
| SCHEMBL11050544 | 0.75 | KDM4E (0.74) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL1004350 | 0.75 | KMT2A (0.59) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL21771871 | 0.75 | KMT2A (0.60) | KMT2AALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL20323265 | 0.75 | KMT2A (0.68) | KMT2AALDH1A1HSD17B10MAPTMEN1 | |
| SCHEMBL12608927 | 0.75 | HSD17B10 (0.72) | KMT2AALDH1A1TSHRHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346260-B1 | HETEROCYCLIC ALKYLENEDIONE PHENOLS AND ALKYLENEDIONE PHENYL PHENOL | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-02-12 | — | — | US | disclosed |
| EP-1074179-A2 | Microbicidal active ingredients | Ciba SC Holding AG (CH) | 2001-02-07 | — | — | EP | disclosed |