⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27387715 | 0.83 | — | — | |
| SCHEMBL21194025 | 0.79 | — | — | |
| SCHEMBL11613356 | 0.78 | — | — | |
| SCHEMBL457076 | 0.77 | — | — | |
| SCHEMBL8363320 | 0.77 | — | — | |
| SCHEMBL22032047 | 0.77 | — | — | |
| SCHEMBL11689212 | 0.77 | — | — | |
| SCHEMBL27640438 | 0.76 | PNMT (0.46) | — | |
| SCHEMBL5267769 | 0.76 | — | — | |
| SCHEMBL27621593 | 0.75 | PNMT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002057258-A1 | CYCLO`D!AZEPANE DERIVATIVES WHICH ARE USED AS FARNESYLTRANSFERASE INHIBITORS AND METHOD FOR THE PREPARATION THEREOF | LES LABORATOIRES SERVIER (FR) | 2002-07-25 | — | — | WO | disclosed |