SCHEMBL457076

SCHEMBL457076

CCc1cc[c]cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16684700 0.83 TAAR1 (0.31)
SCHEMBL442844 0.82
SCHEMBL8039475 0.79 CTRC (0.40)
SCHEMBL21194025 0.79
SCHEMBL58401 0.78 GABRA1 (0.33)
SCHEMBL7563567 0.78 LIPG (0.37)
SCHEMBL1355723 0.78 CA1 (0.32)
SCHEMBL22032047 0.77
SCHEMBL8363320 0.77
SCHEMBL7701047 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069679-A N- (substituted phenyl) thiazole phenoxyacetamide compound and preparation method and application thereof 湖南省农业生物技术研究所 2023-11-17 CN claimed
CN-103360264-A Synthesizing method of indacaterol amino fragment 5,6-diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride WUHAN HENGHEDA BIOLOG PHARMACEUTICAL CO LTD 2013-10-23 CN claimed
US-4716168-A STIMULANTS OF IMMUNE RESPONSE NORWICH EATON PHARMACEUTICALS, INC. (US) 1987-12-29 US claimed
EP-0187705-A2 Imidazo(4,5-f)quinolines useful as immunomodulating agents Norwich Eaton Pharmaceuticals, Inc. (US) 1986-07-16 EP claimed
US-4567197-A THORMBOXANE A2 ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-28 US claimed
CN-117069679-A N- (substituted phenyl) thiazole phenoxyacetamide compound and preparation method and application thereof 湖南省农业生物技术研究所 2023-11-17 CN disclosed
EP-3692088-B1 LATENT CATALYSTS WITH CHELATE LIGANDS FOR POLYMERIZATION OF DICYCLOPENTADIENE (DCPD) UNIV STUTTGART (DE) 2023-08-02 EP disclosed
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP disclosed
US-10072036-B2 N-heterocyclic carbene complexes of metal imido alkylidenes and metal OXO alkylidenes, and the use of same Universität Stuttgart (DE) 2018-09-11 US disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
WO-2018021977-A1 GLYCINE METABOLISM MODULATORS AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-02-01 WO disclosed
US-9585392-B2 3-phenylisoxazolin derivatives with herbicidal action BAYER CROPSCIENCE AG (DE) 2017-03-07 US disclosed
US-5166377-A Thromboxane A2 antagonist as coagulants or vasoconstrictors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-11-24 US disclosed
EP-0503099-A1 PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-09-16 EP disclosed
US-4883789-A Substituted phenyltrialkylsilane insecticides FMC CORPORATION (US) 1989-11-28 US disclosed
US-4716168-A STIMULANTS OF IMMUNE RESPONSE NORWICH EATON PHARMACEUTICALS, INC. (US) 1987-12-29 US disclosed
EP-0187705-A2 Imidazo(4,5-f)quinolines useful as immunomodulating agents Norwich Eaton Pharmaceuticals, Inc. (US) 1986-07-16 EP disclosed
US-4567197-A THORMBOXANE A2 ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-28 US disclosed
US-4038396-A ANTIPYRETICS, ANALGESICS MERCK & CO., INC. (US) 1977-07-26 US disclosed
US-3931218-A HYPOGLYCEMIC ANTIRESERPINE, ANTIULCER, OGENIC, ANTIARRHYTHMIA AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US disclosed