Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ADCY6 | O43306 | 3/20 | 0.41 |
| ▸ | ADCY3 | O60266 | 3/20 | 0.41 |
| ▸ | ADCY9 | O60503 | 3/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.41 |
| ▸ | GCGR | P47871 | 3/20 | 0.41 |
| ▸ | ADCY7 | P51828 | 3/20 | 0.41 |
| ▸ | ADCY2 | Q08462 | 3/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 3/20 | 0.41 |
| ▸ | ADCY4 | Q8NFM4 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695335 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2IKBKBMTNR1AMTNR1BGCGR | |
| SCHEMBL7699326 | 0.86 | IKBKB (0.47) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7703333 | 0.84 | KDM4E (0.64) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7701315 | 0.81 | MTNR1A (0.45) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7695163 | 0.81 | KDM4E (0.58) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7699894 | 0.80 | IKBKB (0.54) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7695359 | 0.79 | EPHX2 (0.44) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7704952 | 0.79 | SMN1; SMN2 (0.44) | KDM4EGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7695247 | 0.79 | EPHX2 (0.54) | KDM4EGAASMN1; SMN2RAB9AIKBKB | |
| SCHEMBL7703211 | 0.79 | KDM4E (0.49) | KDM4EGAASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |