Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 2/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695082 | 0.88 | MAPT (0.50) | GAAMEN1KMT2AMAPTSTAT3 | |
| SCHEMBL7701183 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAEPHX2NR1H4MEN1 | |
| SCHEMBL7701315 | 0.85 | MTNR1A (0.45) | SMN1; SMN2GAAMEN1KMT2AMAPT | |
| SCHEMBL7699326 | 0.84 | IKBKB (0.47) | SMN1; SMN2GAAEPHX2NR1H4MEN1 | |
| SCHEMBL7699146 | 0.80 | MAPT (0.57) | SMN1; SMN2GAAMEN1KMT2AMAPT | |
| SCHEMBL7693765 | 0.80 | EPHX2 (0.44) | SMN1; SMN2GAAEPHX2NR1H4MEN1 | |
| SCHEMBL7701807 | 0.80 | IKBKB (0.43) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL7695247 | 0.79 | EPHX2 (0.54) | SMN1; SMN2GAAEPHX2NR1H4MEN1 | |
| SCHEMBL7701097 | 0.79 | KDM4E (0.47) | SMN1; SMN2GAAEPHX2NR1H4MAPT | |
| SCHEMBL7704697 | 0.78 | ADCY8 (0.45) | GAAMEN1KMT2AMAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |