SCHEMBL7701156

SCHEMBL7701156

CCC1CC(c2ccc(O[Si](C)(C)C(C)(C)C)cc2O[Si](C)(C)C(C)(C)C)CCC1(O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.33
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
CA12 O43570 3/20 0.32
CA1 P00915 3/20 0.32
CA9 Q16790 3/20 0.32
FKBP1A P62942 1/20 0.31
ACHE P22303 1/20 0.31
PREP P48147 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6434920 0.81 CA12 (0.37) DRD2HSP90AA1HSP90AB1CA12CA1
SCHEMBL6499014 0.77 CA12 (0.38) HSP90AA1HSP90AB1CA12CA1CA9
SCHEMBL6440743 0.76 DRD2 (0.39) DRD2HSP90AA1HSP90AB1CA12CA1
SCHEMBL6433061 0.76 CA12 (0.37) HSP90AA1HSP90AB1CA12CA1CA9
SCHEMBL6433055 0.76 CA12 (0.37) HSP90AA1HSP90AB1CA12CA1CA9
SCHEMBL6434340 0.74 CA12 (0.39) HSP90AA1HSP90AB1CA12CA1CA9
SCHEMBL6806304 0.73 PREP (0.35) HSP90AA1HSP90AB1CA12CA1CA9
SCHEMBL6493126 0.73 TYR (0.37) DRD2HSP90AB1
SCHEMBL6433948 0.71 CA12 (0.39) DRD2HSP90AA1HSP90AB1CA12CA1
SCHEMBL6433944 0.71 CA12 (0.39) DRD2HSP90AA1HSP90AB1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1165495-A1 RESORCINOL DERIVATIVES PFIZER INC. (US) 2002-01-02 EP disclosed
WO-2000056702-A1 RESORCINOL DERIVATIVES PFIZER INC. (US) 2000-09-28 WO disclosed