Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3223527 | 0.74 | MAP4K4 (0.39) | LMNAPTGDR2 | |
| SCHEMBL11466620 | 0.69 | GABRP (0.33) | CA12CA9KMT2AGAAKDM4E | |
| SCHEMBL28526673 | 0.68 | TSHR (0.49) | CA12CA9KMT2AGAAKDM4E | |
| SCHEMBL6827036 | 0.67 | CA12 (0.64) | NR1H2CA12CA9KMT2AKDM4E | |
| SCHEMBL63779 | 0.67 | KMT2A (0.64) | CA12CA9KMT2AGAALMNA | |
| SCHEMBL3222455 | 0.66 | MAP4K4 (0.39) | LMNA | |
| SCHEMBL8492583 | 0.66 | ALDH1A1 (0.55) | CA12CA9KMT2AGAAKDM4E | |
| SCHEMBL22852765 | 0.66 | KDM4E (0.47) | CA12CA9KMT2AGAAKDM4E | |
| SCHEMBL30294881 | 0.66 | KDM4E (0.47) | CA12CA9KMT2AGAAKDM4E | |
| SCHEMBL28519051 | 0.66 | CA1 (0.50) | PTGS2CA12CA9KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068394-A1 | QUINOLINE DERIVATIVE AS TYROSINE KINASE INHIBITOR | GLAXO GROUP LIMITED (GB) | 2002-09-06 | — | — | WO | disclosed |