Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700807 | 1.00 | PAK4 (0.39) | PAK4SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL7695738 | 1.00 | PAK4 (0.39) | PAK4SMN1; SMN2HPGDGAAMEN1 | |
| SCHEMBL7698467 | 0.75 | KMT2A (0.38) | MEN1KMT2AALDH1A1RAB9AHTT | |
| SCHEMBL8635453 | 0.75 | SIGMAR1 (0.50) | MEN1KMT2ATSHR | |
| SCHEMBL7700290 | 0.69 | KMT2A (0.52) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7695733 | 0.68 | MAPT (0.38) | MEN1KMT2ATP53 | |
| SCHEMBL7700804 | 0.68 | MAPT (0.38) | MEN1KMT2ATP53 | |
| SCHEMBL8119380 | 0.68 | SIGMAR1 (0.58) | MEN1KMT2ATSHR | |
| SCHEMBL7701486 | 0.68 | MAPT (0.38) | MEN1KMT2ATP53 | |
| SCHEMBL5674113 | 0.65 | SIGMAR1 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342511-B1 | RACEMIC, ENANTIOMORPHS AND DIASTERIOMORPHS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-01-29 | — | — | US | disclosed |
| EP-0986555-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055478-A1 | NOVEL PHENCYCLIDINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 1998-12-10 | — | — | WO | disclosed |