Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | PRCP | P42785 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698467 | 0.79 | KMT2A (0.38) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP | |
| SCHEMBL7695738 | 0.75 | PAK4 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL7701489 | 0.75 | PAK4 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL7700807 | 0.75 | PAK4 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL7437101 | 0.70 | SIGMAR1 (0.46) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP | |
| Rolicyclidine SCHEMBL517928 | 0.68 | SIGMAR1 (1.00) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP | |
| Phencyclidine SCHEMBL17008793 | 0.68 | SIGMAR1 (1.00) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP | |
| SCHEMBL9153279 | 0.68 | SIGMAR1 (1.00) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP | |
| Phencyclidine SCHEMBL42022 | 0.68 | SIGMAR1 (1.00) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP | |
| SCHEMBL23595707 | 0.67 | SIGMAR1 (0.55) | SIGMAR1GRIN1GRIN2AGRIN2BPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846980-A | N-(benzhydryloxyalkyl)-4-(carboxy/carbamoyl methyl)-piperidine derivatives as antidepressants | COOPERATION PHARMACEUTIQUE FRANCAISE (FR) | 1998-12-08 | — | — | US | disclosed |