Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 5/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698505 | 0.89 | FYN (0.39) | HTTMAPTEIF2AK3SLC29A1RET | |
| SCHEMBL7696372 | 0.88 | ADORA2A (0.48) | HTTRETADORA2API4KAPI4K2B | |
| SCHEMBL7701572 | 0.87 | EIF2AK3 (0.37) | KMT2AMEN1POLBHTTMAPT | |
| SCHEMBL7704457 | 0.86 | FLT3 (0.41) | RETPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7705468 | 0.86 | EGFR (0.43) | SLC29A1RIPK2SRCNSD3 | |
| SCHEMBL7700275 | 0.82 | CFD (0.47) | POLBHTTMAPTEIF2AK3RET | |
| SCHEMBL7697687 | 0.81 | RIPK1 (0.42) | POLBHTTMAPTEIF2AK3RET | |
| SCHEMBL7704465 | 0.78 | EIF2AK3 (0.40) | HTTEIF2AK3RIPK2KDM4ELMNA | |
| SCHEMBL7701507 | 0.77 | ADORA2A (0.50) | HTTADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL17406909 | 0.75 | RPS6KB1 (0.41) | HTTMAPTRETRIPK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |