Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704697 | 0.92 | ADCY8 (0.45) | KDM4EGAAIKBKBTRPV1DGAT1 | |
| SCHEMBL7693922 | 0.91 | KDM4E (0.60) | KDM4EGAADGAT1NPC1RAB9A | |
| SCHEMBL7693950 | 0.86 | IKBKB (0.52) | KDM4EGAAIKBKBTRPV1TP53 | |
| SCHEMBL7703333 | 0.86 | KDM4E (0.64) | KDM4EGAAIKBKBTRPV1DGAT1 | |
| SCHEMBL7695082 | 0.84 | MAPT (0.50) | KDM4EGAAIKBKBTRPV1DGAT1 | |
| SCHEMBL7699293 | 0.83 | KDM4E (0.53) | KDM4EGAADGAT1MEN1KMT2A | |
| SCHEMBL7697491 | 0.83 | HDAC4 (0.49) | IKBKBTRPV1DGAT1MAPT | |
| SCHEMBL7699894 | 0.82 | IKBKB (0.54) | KDM4EGAAIKBKBNPC1RAB9A | |
| SCHEMBL7695211 | 0.82 | KDM4E (0.53) | KDM4EGAAIKBKBTRPV1DGAT1 | |
| SCHEMBL7698068 | 0.82 | KDM4E (0.47) | KDM4EGAAIKBKBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |