Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY8 | P40145 | 1/20 | 0.45 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699293 | 0.92 | KDM4E (0.53) | ADCY8ADCY1TMPRSS4KDM4EGAA | |
| SCHEMBL7701545 | 0.92 | KDM4E (0.48) | KDM4EGAADGAT1P2RX1MAPT | |
| SCHEMBL7695082 | 0.88 | MAPT (0.50) | KDM4EGAADGAT1RXFP1MAPT | |
| SCHEMBL7695533 | 0.84 | ADCY8 (0.47) | ADCY8ADCY1TMPRSS4KDM4EDGAT1 | |
| SCHEMBL7693922 | 0.84 | KDM4E (0.60) | KDM4EGAADGAT1P2RX1MEN1 | |
| SCHEMBL7699146 | 0.82 | MAPT (0.57) | KDM4EGAARXFP1MAPTMEN1 | |
| SCHEMBL7698685 | 0.81 | DGAT1 (0.50) | ADCY8ADCY1TMPRSS4KDM4EDGAT1 | |
| SCHEMBL7703333 | 0.80 | KDM4E (0.64) | KDM4EGAADGAT1MAPTALDH1A1 | |
| SCHEMBL7693950 | 0.80 | IKBKB (0.52) | KDM4EGAAMAPTIKBKBTRPV1 | |
| SCHEMBL7699576 | 0.80 | KDM4E (0.48) | KDM4EGAARXFP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |