Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794102 | 0.89 | ALDH1A1 (0.50) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL14565683 | 0.88 | MAPT (0.39) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL29894560 | 0.87 | MAPT (0.35) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL14142621 | 0.84 | ALDH1A1 (0.43) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL21356995 | 0.84 | GRM5 (0.46) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL21319248 | 0.82 | ALDH1A1 (0.35) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL30018540 | 0.82 | MAPT (0.35) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL97296 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL3763790 | 0.80 | MAPT (0.40) | MAPTALDH1A1GAATSHRSMN1; SMN2 | |
| SCHEMBL1330188 | 0.80 | ALDH1A1 (0.40) | MAPTALDH1A1GAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8679621-B2 | Materials and methods for autonomous restoration of electrical conductivity | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-03-25 | — | — | US | claimed |
| US-20120067615-A1 | Materials and Methods for Autonomous Restoration of Electrical Conductivity | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-03-22 | — | — | US | claimed |
| US-8846404-B2 | System for visual indication of mechanical damage | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-09-30 | — | — | US | disclosed |
| US-8679621-B2 | Materials and methods for autonomous restoration of electrical conductivity | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-03-25 | — | — | US | disclosed |
| US-20120196373-A1 | System For Visual Indication Of Mechanical Damage | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120067615-A1 | Materials and Methods for Autonomous Restoration of Electrical Conductivity | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-03-22 | — | — | US | disclosed |