Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532261 | 0.82 | ALDH1A1 (0.33) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL7279573 | 0.80 | MAPT (0.40) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL9666898 | 0.80 | MAPT (0.40) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL14142621 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL770158 | 0.80 | MAPT (0.43) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL133465 | 0.80 | MAPT (0.37) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL1980636 | 0.79 | GAA (0.39) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL5167168 | 0.79 | ALDH1A1 (0.31) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL2904764 | 0.76 | MAPT (0.40) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL3763790 | 0.76 | MAPT (0.40) | ALDH1A1MAPTGAATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621958-B | Single-stranded DNA aptamer sequence for specifically recognizing ATP and application thereof | 江南大学 | 2023-09-22 | — | — | CN | claimed |
| CN-110003835-A | Anchor Agent and its preparation and application for railway maintenance | 湖北坤能科技有限公司 | 2019-07-12 | — | — | CN | claimed |
| CN-106311328-A | Method for preparing catalyst for synthesis of polyoxymethylene dimethyl ether | 江苏色可赛思树脂有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-106257977-A | Composite polyamide membrane post-treated with nitrous acid | 陶氏环球技术有限责任公司 | 2016-12-28 | — | — | CN | claimed |
| CN-104292445-B | A kind of preparation method of macromole p-(dimethylamino)-benzoic acid ester type compound | 山东久日化学科技有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | claimed |
| CN-104292445-A | Preparation method for macromolecular p-dimethylamino benzoate compound | SHANDONG JIURI CHEMICAL TECHNOLOGY CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-103102314-A | Benzothiazole, benzimidazole, benzoxazole derivatives and preparation method and application thereof | UNIV SICHUAN | 2013-05-15 | — | — | CN | claimed |
| CN-102039100-A | Amphipathic graft polymer pigment dispersing agent and synthesis process thereof | WUHAN INST TECHNOLOGY | 2011-05-04 | — | — | CN | claimed |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | PFIZER INC. | 2007-09-27 | — | — | US | claimed |
| CN-1323209-A | Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase | SCIOS INC (US) | 2001-11-21 | — | — | CN | claimed |
| EP-1107758-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2001-06-20 | — | — | EP | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-2000012074-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2000-03-09 | — | — | WO | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| CN-1018907-B | Pressure-sensitive carbon paper and production method thereof | ZHU HUA (CN) | 1992-11-04 | — | — | CN | claimed |
| US-4952585-A | Castanospermine esters in the inhibition of tumor metastasis | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-28 | — | — | US | claimed |
| US-4908204-A | Reversibly blocked plasmin, t-PA hybrid fibrinolytic enzymes and pharmaceutical compositions and anti-thrombotic use thereof | BEECHAM GROUP P.L.C. (GB) | 1990-03-13 | — | — | US | claimed |
| CN-1038972-A | A kind of pressure-sensing carbon paper and production method thereof | ZHU HUA (CN) | 1990-01-24 | — | — | CN | claimed |
| EP-0155387-B1 | FIBRONOLYTICALLY ACTIVE HYBRID PROTEIN, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION | BEECHAM GROUP PLC (GB) | 1989-09-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | CNKSR1, IL1RN, CHUK | ALDH1A1 945/4885MAPT 3392/4885GAA 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.