Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.31 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605603 | 0.84 | LMNA (0.33) | NQO1MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL7706745 | 0.81 | HSP90AB1 (0.48) | MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1POLQ | |
| SCHEMBL7608589 | 0.80 | LMNA (0.36) | NQO1MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL7789607 | 0.79 | HSP90AB1 (0.33) | NQO1MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL7792730 | 0.79 | LMNA (0.32) | MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1POLQ | |
| SCHEMBL7784152 | 0.79 | LMNA (0.35) | NQO1MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL7612818 | 0.78 | ALDH1A1 (0.43) | MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1POLQ | |
| SCHEMBL6942331 | 0.78 | LMNA (0.37) | NQO1MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1 | |
| SCHEMBL8381251 | 0.77 | KDM4E (0.39) | MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1POLQ | |
| SCHEMBL7784140 | 0.75 | LMNA (0.33) | MAP1LC3BMAP1LC3AHSP90AA1HSP90AB1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350733-B1 | 4-HYDROXYBENZOPYRAN-2-ONE DERIVATIVES; BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS; SKIN DISORDERS | AVENTIS PHARMA S.A. (FR) | 2002-02-26 | — | — | US | disclosed |
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |