Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880698 | 0.82 | CHRNA7 (0.67) | HTR3A | |
| SCHEMBL7686167 | 0.78 | CHRNA7 (0.51) | HTR3A | |
| SCHEMBL5268531 | 0.78 | HTR3A (0.61) | HTR3A | |
| SCHEMBL7644363 | 0.77 | CHRNA7 (0.51) | — | |
| SCHEMBL7601725 | 0.77 | HTR3A (0.52) | HTR3A | |
| SCHEMBL7438039 | 0.76 | — | — | |
| SCHEMBL7695932 | 0.76 | CHRNA7 (0.53) | — | |
| SCHEMBL7692924 | 0.75 | CHRNA7 (0.49) | HTR3A | |
| SCHEMBL14027668 | 0.74 | HTR3A (0.52) | HTR3A | |
| SCHEMBL7438929 | 0.74 | TAS1R3 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016357-A2 | QUINUCLIDINE-SUBSTITUTED ARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |