Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.36 |
| ▸ | ABL1 | P00519 | 5/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | HCK | P08631 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 4/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 4/20 | 0.36 |
| ▸ | PRKDC | P78527 | 4/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991124 | 0.87 | PI4KB (0.35) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL8991004 | 0.86 | YTHDC1 (0.31) | SRCEGFR | |
| SCHEMBL7703318 | 0.86 | RET (0.39) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL7700288 | 0.82 | KDM4E (0.44) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL7701709 | 0.77 | RET (0.36) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL8991135 | 0.77 | KDM4E (0.35) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL8991011 | 0.76 | KDM4E (0.49) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL7697510 | 0.75 | LRRK2 (0.58) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL7700980 | 0.74 | NPC1 (0.45) | SRCABL1KDRPIK3CDEGFR | |
| SCHEMBL8991414 | 0.74 | KDM4E (0.57) | SRCABL1KDRPIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |