Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 2/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 6/20 | 0.34 |
| ▸ | RET | P07949 | 5/20 | 0.34 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | ABL1 | P00519 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | HCK | P08631 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701707 | 0.87 | SRC (0.36) | PI4KBADORA2AADORA1KDM4ETSHR | |
| SCHEMBL8991118 | 0.86 | RET (0.38) | RET | |
| SCHEMBL8991163 | 0.86 | YTHDC1 (0.31) | SRCEGFR | |
| SCHEMBL8990961 | 0.82 | KDM4E (0.44) | PI4KBADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8991135 | 0.77 | KDM4E (0.35) | PI4KBADORA2AADORA1KDM4ETSHR | |
| SCHEMBL7701709 | 0.77 | RET (0.36) | PI4KBKDM4ETSHRMAPK1HTT | |
| SCHEMBL7697510 | 0.75 | LRRK2 (0.58) | PI4KBADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8991251 | 0.75 | KDM4E (0.49) | ADORA2AADORA1KDM4ETSHRMAPK1 | |
| SCHEMBL8991267 | 0.75 | KDM4E (0.48) | PI4KBPI4KAPI4K2BPI4K2AKDM4E | |
| SCHEMBL7703236 | 0.74 | ADK (0.38) | PI4KBADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |