Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL609797 | 0.81 | SHBG (0.38) | — | |
| SCHEMBL609535 | 0.81 | SHBG (0.38) | — | |
| SCHEMBL9118328 | 0.81 | SHBG (0.38) | — | |
| SCHEMBL612009 | 0.81 | SHBG (0.38) | — | |
| SCHEMBL9118331 | 0.81 | SHBG (0.38) | — | |
| SCHEMBL9114377 | 0.78 | PLA2G1B (0.31) | PLA2G1BATG4B | |
| SCHEMBL9119013 | 0.78 | PLA2G1B (0.31) | PLA2G1BATG4B | |
| SCHEMBL14398026 | 0.73 | L3MBTL1 (0.33) | L3MBTL1PLA2G1BATG4B | |
| SCHEMBL18670445 | 0.73 | L3MBTL1 (0.33) | L3MBTL1PLA2G1BATG4B | |
| SCHEMBL50282 | 0.73 | L3MBTL1 (0.33) | L3MBTL1PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348616-B1 | CHEMICAL INTERMEDIATES FOR SYNTHESIS OF DESIRED BENZOXAZINONES | PIERCE MICHAEL ERNEST (US) | 2002-02-19 | — | — | US | disclosed |
| US-6147210-A | Practical synthesis of benzoxazinones useful as HIV reverse transcriptase inhibitors | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-11-14 | — | — | US | disclosed |
| WO-1998004535-A1 | A PRACTICAL SYNTHESIS OF BENZOXAZINONES USEFUL AS HIV REVERSE TRANSCRIPTASE INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |