Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464472 | 0.91 | NPC1 (0.40) | CNR2NPC1RAB9AF2RPOLB | |
| SCHEMBL8773778 | 0.91 | NPC1 (0.40) | CNR2NPC1RAB9AF2RPOLB | |
| SCHEMBL30485788 | 0.91 | NPC1 (0.40) | CNR2NPC1RAB9AF2RPOLB | |
| SCHEMBL6834699 | 0.89 | CNR2 (0.32) | CNR2NPC1RAB9ACNR1 | |
| SCHEMBL2955109 | 0.89 | NPC1 (0.42) | NPC1RAB9AMAOBPOLBLMNA | |
| SCHEMBL101432 | 0.89 | CNR2 (0.39) | CNR2CNR1MAOBMAOAKDM4E | |
| SCHEMBL12774889 | 0.87 | NPC1 (0.40) | NPC1RAB9AMAOBPOLBLMNA | |
| SCHEMBL1923121 | 0.86 | NPC1 (0.40) | NPC1RAB9AMAOBPOLBLMNA | |
| SCHEMBL4594117 | 0.86 | CYP3A4 (0.35) | NPC1RAB9AMAOBPOLBLMNA | |
| SCHEMBL23533531 | 0.85 | CNR2 (0.41) | CNR2CNR1MAOBLMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177182-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | Ciba SC Holding AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| EP-1086145-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| WO-2000068218-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-11-16 | — | — | WO | disclosed |
| WO-1999062961-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-12-09 | — | — | WO | disclosed |