Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153580 | 0.85 | ABCB1 (0.51) | ABCB1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL29087910 | 0.84 | ABCB1 (0.52) | ABCB1ALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL29087914 | 0.84 | ABCB1 (0.52) | ABCB1ALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL6154183 | 0.82 | ABCB1 (0.48) | ABCB1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL6154182 | 0.82 | ABCB1 (0.48) | ABCB1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL1549936 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1KMT2ASLC6A2 | |
| SCHEMBL7705289 | 0.79 | ALDH1A1 (0.54) | ABCB1ALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL13936261 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1KMT2ATRPM8 | |
| SCHEMBL10010416 | 0.78 | TSHR (0.39) | ABCB1KMT2A | |
| SCHEMBL14721367 | 0.78 | ABCB1 (0.45) | ABCB1ALDH1A1MAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469193-B1 | THREE COMPONENT COUPLINGS OF ALIPHATIC ALCOHOLS, ALKYL HALIDES AND CARBON DIOXIDE IN THE PRESENCE OF CESIUM CARBONATE AND TETRABUTYLAMMONIUM IODIDE | UNIVERSITY OF SOUTH FLORIDA | 2002-10-22 | — | — | US | disclosed |
| WO-2000050376-A9 | EFFICIENT SYNTHESIS OF ALKYL CARBONATES | UNIV SOUTH FLORIDA (US) | 2001-10-11 | — | — | WO | disclosed |
| WO-2000050376-A2 | EFFICIENT SYNTHESIS OF ALKYL CARBONATES | UNIVERSITY OF SOUTH FLORIDA (US) | 2000-08-31 | — | — | WO | disclosed |