Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852397 | 0.82 | SLC15A1 (0.46) | ALDH1A1MAPK1L3MBTL1SLC15A1ABCB1 | |
| SCHEMBL16408022 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 | |
| SCHEMBL7701759 | 0.79 | ABCB1 (0.52) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL6154936 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 | |
| SCHEMBL18914889 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 | |
| SCHEMBL19852396 | 0.79 | SLC15A1 (0.44) | ALDH1A1MAPK1L3MBTL1SLC15A1CDC25B | |
| SCHEMBL18206809 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 | |
| SCHEMBL5030099 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 | |
| SCHEMBL16399030 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 | |
| SCHEMBL673677 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1SLC15A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469193-B1 | THREE COMPONENT COUPLINGS OF ALIPHATIC ALCOHOLS, ALKYL HALIDES AND CARBON DIOXIDE IN THE PRESENCE OF CESIUM CARBONATE AND TETRABUTYLAMMONIUM IODIDE | UNIVERSITY OF SOUTH FLORIDA | 2002-10-22 | — | — | US | disclosed |