Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372509 | 0.97 | TSHR (0.38) | TSHR | |
| SCHEMBL16112892 | 0.84 | TSHR (0.35) | TSHR | |
| SCHEMBL372795 | 0.78 | DNM1 (0.41) | TSHR | |
| SCHEMBL372674 | 0.75 | OPRM1 (0.50) | TSHR | |
| SCHEMBL5948626 | 0.73 | TSHR (0.36) | TSHR | |
| SCHEMBL12344858 | 0.73 | — | — | |
| SCHEMBL986680 | 0.73 | — | — | |
| SCHEMBL14175020 | 0.73 | — | — | |
| SCHEMBL23967577 | 0.73 | — | — | |
| SCHEMBL372363 | 0.73 | OPRM1 (0.48) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| WO-2000042043-A1 | PYRROLO[2,3-d]PYRIMIDINES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-07-20 | — | — | WO | disclosed |