Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21523578 | 0.82 | TSHR (0.36) | TSHR | |
| SCHEMBL17715736 | 0.82 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL629544 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL3374702 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL1244564 | 0.77 | — | — | |
| SCHEMBL29210930 | 0.74 | — | — | |
| Ethylamine SCHEMBL27872574 | 0.74 | TSHR (0.36) | TSHR | |
| SCHEMBL3372731 | 0.74 | TDP1 (0.33) | — | |
| SCHEMBL4983461 | 0.73 | ALOX15 (0.45) | TSHR | |
| SCHEMBL6544163 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056716-B1 | CYCLOHEXANEDIOLE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| US-6184422-B1 | TREATMENT AND PREVENTION OF HYPERPROLIFERATIVE SKIN DISEASES; REVERSING CONDITIONS ASSOCIATED WITH PHOTODAMAGE; ANTITUMOR, -CARCINOGENIC AGENTS; PSORIASIS; DISORDERS OF NEOPLASTIC DISEASES; KERATINIZATION/KERATOSIS; ACNE; SEBORRHEA | HOFFMAN-LA ROCHE INC. | 2001-02-06 | — | — | US | disclosed |