⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583453 | 0.81 | GDA (0.57) | — | |
| SCHEMBL18251 | 0.81 | PNP (0.62) | — | |
| SCHEMBL27775482 | 0.80 | XDH (0.61) | — | |
| SCHEMBL1394088 | 0.80 | PNP (0.61) | — | |
| SCHEMBL17554279 | 0.79 | XDH (0.63) | — | |
| SCHEMBL27496341 | 0.78 | GDA (0.62) | — | |
| SCHEMBL27503507 | 0.78 | XDH (0.62) | — | |
| Cyanide SCHEMBL2694132 | 0.78 | PNP (0.58) | — | |
| SCHEMBL5198603 | 0.77 | GDA (0.61) | — | |
| SCHEMBL1286951 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525726-A | Process for the preparation of an antiviral agent | E. R. SQUIBB & SONS, INC. (US) | 1996-06-11 | — | — | US | claimed |
| US-5516903-A | Process for preparing [IR-(1α,2β-3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one | E. R. SQUIBB & SONS, INC. (US) | 1996-05-14 | — | — | US | claimed |
| CN-117924514-B | Probe system for detecting cholesterol and application thereof | 重庆医科大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-117924514-A | Probe system for detecting cholesterol and application thereof | 重庆医科大学 | 2024-04-26 | — | — | CN | disclosed |
| US-6353122-B1 | IN CYCLOHEXANONE WITH POTASSIUM PEROXYMONOSULFATE AND SUBSEQUENT REARRANGEMENT TO PROVIDE THE CORRESPONDING CYCLOBUTANONE | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-05 | — | — | US | disclosed |
| CN-1040426-C | Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol | SQUIBB & SONS INC (US) | 1998-10-28 | — | — | CN | disclosed |
| WO-1998038184-A1 | A METHOD FOR EPOXIDATION OF 3-METHYLENECYCLOPROPANES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |
| EP-0535448-B1 | Process and intermediates for the preparation of an antiviral agent containing a cyclobutyl group | SQUIBB & SONS INC (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5525726-A | Process for the preparation of an antiviral agent | E. R. SQUIBB & SONS, INC. (US) | 1996-06-11 | — | — | US | disclosed |
| US-5516903-A | Process for preparing [IR-(1α,2β-3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one | E. R. SQUIBB & SONS, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5412134-A | Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol | E. R. SQUIBB & SONS, INC. (US) | 1995-05-02 | — | — | US | disclosed |
| CN-1082025-A | 2 of two protections, the preparation method of 3-methylol cyclobutanol | SQUIBB & SONS INC (US) | 1994-02-16 | — | — | CN | disclosed |
| EP-0572209-A2 | Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol | E.R. SQUIBB & SONS, INC. (US) | 1993-12-01 | — | — | EP | disclosed |
| US-5237095-A | Process for the preparation of an antiviral agent | E. R. SQUIBB & SONS, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| US-5237096-A | Process for the preparation of an antiviral agent | E. R. SQUIBB & SONS, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| US-5233086-A | Intermediates for the preparation of an antiviral agent | E. R. SQUIBB & SONS, INC. (US) | 1993-08-03 | — | — | US | disclosed |
| US-5218142-A | Process for the preparation of an antiviral agent | E. R. SQUIBB & SONS, INC. (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0535448-A2 | Process and intermediates for the preparation of an antiviral agent containing a cyclobutyl group | E.R. SQUIBB & SONS, INC. (US) | 1993-04-07 | — | — | EP | disclosed |
| US-5185463-A | PROCESS FOR THE PREPARATION OF AN ANTIVIRAL AGENT | E. R. SQUIBB & SONS, INC. (US) | 1993-02-09 | — | — | US | disclosed |