SCHEMBL7702173

SCHEMBL7702173

O=S(=O)(Nc1cc(Cl)c(O)c(Cl)c1Cl)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.69
ALOX15 P16050 3/20 0.69
HSD17B10 Q99714 3/20 0.69
ALDH1A1 P00352 3/20 0.69
MEN1 O00255 2/20 0.69
KMT2A Q03164 2/20 0.69
HPGD P15428 1/20 0.69
EP300 Q09472 1/20 0.60
TSHR P16473 2/20 0.59
HSP90AA1 P07900 2/20 0.57
ERBB2 P04626 1/20 0.57
HSP90AB1 P08238 1/20 0.57
HTT P42858 2/20 0.57
PKM P14618 1/20 0.57
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
ADAM17 P78536 1/20 0.53
KLF5 Q13887 1/20 0.53
GFER P55789 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10619794 0.87 GAA (0.82) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL13510376 0.86 EP300 (0.80) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL1151730 0.83 ERBB2 (0.59) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL6806783 0.81 GAA (0.72) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL6803322 0.81 GAA (0.60) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL5694590 0.79 ERBB2 (0.59) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL1151729 0.79 GAA (0.80) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL13510382 0.78 EP300 (0.80) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL11785794 0.78 GAA (0.56) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL7573482 0.78 ERBB2 (0.60) GAAALOX15HSD17B10ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6380146-B1 FOR BLEACHING STAINS ON FABRICS DURING WASHING, WITHOUT PROVOKING DYE DAMAGE UNILEVER HOME & PERSONAL CARE USA A DIVISION OF CONOPCO, INC. 2002-04-30 US claimed
EP-1187899-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2002-03-20 EP claimed
WO-2001000768-A1 BLEACHING DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-01-04 WO claimed
WO-2001000769-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2001-01-04 WO claimed
US-20120100609-A1 N-LINKED GLYCAN BIOSYNTHESIS MODULATORS BIOMARIN PHARMACEUTICAL INC. 2012-04-26 US disclosed
US-6380146-B1 FOR BLEACHING STAINS ON FABRICS DURING WASHING, WITHOUT PROVOKING DYE DAMAGE UNILEVER HOME & PERSONAL CARE USA A DIVISION OF CONOPCO, INC. 2002-04-30 US disclosed
EP-1187899-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2002-03-20 EP disclosed
US-6323014-B1 USED FOR REMOVING COLOURED STAINS FROM FABRICS BY WASHING UNILEVER HOME & PERSONAL CARE DIVISION OF CONOPCO, INC. 2001-11-27 US disclosed
WO-2001000768-A1 BLEACHING DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-01-04 WO disclosed
WO-2001000769-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120100609-A1 N-LINKED GLYCAN BIOSYNTHESIS MODULATORS ENGASE, GALNT1, GALNT13 GAA 98/4885ALOX15 3238/4885HSD17B10 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.