Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 7/20 | 0.56 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | MMP13 | P45452 | 7/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934315 | 0.91 | MMP1 (0.63) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6932216 | 0.89 | MMP1 (0.57) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6932212 | 0.89 | MMP1 (0.57) | MMP1MMP9MMP13CA12CA1 | |
| Hydroxyamine SCHEMBL7644234 | 0.84 | MMP9 (0.65) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6929326 | 0.83 | MMP1 (0.68) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6928585 | 0.82 | MMP9 (0.67) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6927193 | 0.82 | MMP9 (0.72) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6934138 | 0.82 | MMP1 (0.59) | MMP1MMP9MMP13CA12CA1 | |
| SCHEMBL6932228 | 0.81 | MMP9 (0.65) | MMP1MMP9MMP13ADAM17POLB | |
| SCHEMBL6932221 | 0.81 | MMP9 (0.65) | MMP1MMP9MMP13ADAM17POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |