Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702629 | 0.80 | PGR (0.33) | CYP19A1PGRNR3C2AR | |
| SCHEMBL6244893 | 0.79 | SERPINA6 (0.41) | CYP19A1PGRAR | |
| SCHEMBL8083275 | 0.75 | CYP19A1 (0.49) | CYP19A1 | |
| SCHEMBL8083240 | 0.74 | CYP19A1 (0.49) | CYP19A1 | |
| SCHEMBL7796339 | 0.74 | CYP19A1 (0.48) | CYP19A1 | |
| SCHEMBL7115110 | 0.73 | LMNA (0.55) | CYP19A1PGR | |
| SCHEMBL9616583 | 0.72 | CYP19A1 (0.36) | CYP19A1PGRNR3C2AR | |
| SCHEMBL3647269 | 0.72 | CYP19A1 (0.37) | CYP19A1PGRNR3C2AR | |
| SCHEMBL8382698 | 0.72 | LMNA (0.40) | CYP19A1PGRAR | |
| SCHEMBL8376991 | 0.71 | AR (0.35) | PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212345-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | Akzo Nobel N.V. (NL) | 2002-06-12 | — | — | EP | claimed |
| WO-2000059920-A2 | ORALLY ACTIVE 7.ALPHA.-ALKYL ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-10-12 | — | — | WO | claimed |