Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699895 | 0.92 | KMT2A (0.42) | KDM4ENPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL7519093 | 0.88 | PTPN1 (0.46) | KDM4EHDAC1HDAC2FLT3NPC1 | |
| SCHEMBL7702006 | 0.87 | KDM4E (0.46) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7536896 | 0.86 | KDM4E (0.41) | KDM4EHDAC1HDAC2FLT3NPC1 | |
| SCHEMBL7861252 | 0.84 | HDAC1 (0.44) | KDM4EHDAC1HDAC2FLT3NPC1 | |
| SCHEMBL7555860 | 0.80 | AKR1C2 (0.37) | KDM4EHDAC1HDAC2NPC1CYP2C9 | |
| SCHEMBL7553313 | 0.80 | KDM4E (0.43) | KDM4EHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL7694099 | 0.79 | KDM4E (0.49) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7694101 | 0.79 | KDM4E (0.49) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL7526850 | 0.79 | PTPN1 (0.46) | KDM4ENPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |