Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PLD2 | O14939 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694099 | 1.00 | KDM4E (0.49) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7702006 | 0.90 | KDM4E (0.46) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7699895 | 0.87 | KMT2A (0.42) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7855442 | 0.86 | KDM4E (0.55) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7698367 | 0.85 | KDM4E (0.50) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7699527 | 0.85 | KDM4E (0.50) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7516893 | 0.84 | PTPN1 (0.50) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7702706 | 0.79 | KDM4E (0.41) | KDM4EHSD17B10HPGDALDH1A1KMT2A | |
| SCHEMBL7096725 | 0.79 | PTPN1 (0.58) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7096724 | 0.79 | PTPN1 (0.58) | KDM4EHSD17B10HPGDSCN4ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |