Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | LOX | P28300 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694580 | 0.92 | MEN1 (0.52) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7696726 | 0.92 | MEN1 (0.45) | MEN1KMT2ANPC1ENPP3ENPP1 | |
| SCHEMBL7695264 | 0.84 | MEN1 (0.50) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7702735 | 0.83 | UBE2N (0.60) | MEN1KMT2ANPC1ENPP3ENPP1 | |
| SCHEMBL7696727 | 0.82 | MAPT (0.51) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7663107 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7695229 | 0.76 | KDM4E (0.56) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7694582 | 0.75 | UBE2N (0.69) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7695265 | 0.74 | UBE2N (0.56) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL7700431 | 0.72 | TP53 (0.47) | MEN1KMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |