Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694670 | 0.89 | MAPT (0.48) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7663107 | 0.86 | ALDH1A1 (0.47) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7694684 | 0.81 | TP53 (0.65) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7700433 | 0.81 | KMT2A (0.69) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7696409 | 0.78 | KMT2A (0.43) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7695229 | 0.77 | KDM4E (0.56) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7695101 | 0.77 | ALDH1A1 (0.46) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7696673 | 0.77 | ALDH1A1 (0.58) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7700535 | 0.77 | KMT2A (0.52) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7696411 | 0.77 | MEN1 (0.44) | TP53SMN1; SMN2ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |