Biphenyl

Biphenyl

SCHEMBL7702880

CC(C)(C)c1ccc(O)cc1.S.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.70
TYR P14679 1/20 0.70
ESR1 P03372 6/20 0.59
ESR2 Q92731 5/20 0.59
CYP3A4 P08684 2/20 0.59
ALDH1A1 P00352 1/20 0.59
MMP3 P08254 1/20 0.58
BCL2L1 Q07817 1/20 0.58
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KIF11 P52732 3/20 0.46
HSD17B2 P37059 1/20 0.44
UQCRB P14927 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7702949 0.98 LMNA (0.73) LMNATYRESR1ESR2CYP3A4
SCHEMBL3664594 0.96 LMNA (0.70) LMNATYRESR1ESR2CYP3A4
Formaldehyde SCHEMBL28589440 0.90 LMNA (0.61) LMNATYRESR1ESR2CYP3A4
Phenol SCHEMBL875409 0.89 LMNA (0.80) LMNATYRESR1ESR2CYP3A4
Phenol SCHEMBL28166105 0.89 LMNA (0.80) LMNATYRESR1ESR2CYP3A4
SCHEMBL1765333 0.86 LMNA (0.84) LMNATYRESR1ESR2CYP3A4
Phenol SCHEMBL28257274 0.86 LMNA (0.75) LMNATYRESR1ESR2CYP3A4
Hydrogen Sulfide SCHEMBL1975873 0.86 LMNA (0.94) LMNATYRESR1ESR2CYP3A4
Hydrogen Sulfide SCHEMBL10324233 0.86 LMNA (0.94) LMNATYRESR1ESR2CYP3A4
Hydrogen Sulfide SCHEMBL20597835 0.86 LMNA (0.94) LMNATYRESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed