Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708821 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3HPGD | |
| SCHEMBL7711821 | 0.85 | ADORA2A (0.54) | ADORA2AADORA3 | |
| SCHEMBL7703218 | 0.83 | NOTUM (0.37) | ADORA2A | |
| SCHEMBL7705869 | 0.81 | ADORA2A (0.56) | ADORA2AHPGD | |
| SCHEMBL7703193 | 0.80 | ADORA2A (0.46) | ADORA2AADORA3HPGD | |
| SCHEMBL7703126 | 0.78 | ADORA2A (0.53) | ADORA2AADORA3HPGD | |
| SCHEMBL7708984 | 0.78 | ADORA2A (0.49) | ADORA2AADORA3 | |
| SCHEMBL7703027 | 0.78 | ADORA2A (0.51) | ADORA2AADORA3HPGD | |
| SCHEMBL7703024 | 0.78 | ADORA2A (0.49) | ADORA2AADORA3HPGD | |
| SCHEMBL7490670 | 0.76 | ADORA2A (0.62) | ADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |