Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711821 | 0.88 | ADORA2A (0.54) | ADORA2AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7708821 | 0.88 | ADORA2A (0.54) | ADORA2AKDM4EMAPTHPGDGAA | |
| SCHEMBL7711750 | 0.88 | ADORA2A (0.57) | ADORA2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7703126 | 0.87 | ADORA2A (0.53) | ADORA2AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL7711618 | 0.83 | ADORA2A (0.60) | ADORA2AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7708427 | 0.83 | ADORA2A (0.53) | ADORA2ANPC1RAB9A | |
| SCHEMBL7708984 | 0.82 | ADORA2A (0.49) | ADORA2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7702990 | 0.81 | ADORA2A (0.50) | ADORA2AHPGD | |
| SCHEMBL7490670 | 0.81 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL7703027 | 0.80 | ADORA2A (0.51) | ADORA2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |