Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.73 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349443 | 0.94 | KMT2A (0.69) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL693914 | 0.94 | KMT2A (0.69) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL28847414 | 0.93 | KMT2A (0.67) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL31717956 | 0.93 | KMT2A (0.67) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL28162855 | 0.93 | KMT2A (0.67) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL22365668 | 0.86 | CA1 (0.59) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL28455072 | 0.86 | PLA2G2A (0.58) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL6974845 | 0.85 | PTGS2 (0.72) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL6981356 | 0.85 | PTGS2 (0.72) | PLA2G2APLA2G4AKMT2AMEN1CA1 | |
| SCHEMBL5246895 | 0.85 | MEN1 (0.71) | PLA2G2APLA2G4AKMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824642-B | Chrysin phenylalanine derivative with anti-lung cancer activity | 南华大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-113456533-A | Whitening facial cleanser containing baicalin-arbutin micelles | 上海应用技术大学 | 2021-10-01 | — | — | CN | disclosed |
| WO-2021046388-A1 | COMPOSITIONS AND METHODS FOR COGNITIVE PROTECTION OF POLLINATORS AGAINST PESTICIDES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-03-11 | — | — | WO | disclosed |
| CN-109734692-B | Chrysin leucine derivative with EGFR kinase inhibitory activity | 南华大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-109689060-A | combination chemotherapy | 系统肿瘤学有限公司 | 2019-04-26 | — | — | CN | disclosed |
| US-6346255-B1 | PAD FOR IMPROVING SKIN APPEARANCE WITH BACKING, RELEASE LAYERAND VEHICLE | LAVIPHARM LABORATORIES INC. | 2002-02-12 | — | — | US | disclosed |
| WO-1999036032-A1 | PLANT POLAR LIPID PERMEATION ENHANCER IN A COSMETIC PAD FOR IMPROVING SKIN APPEARANCE | LAVIPHARM LABORATORIES, INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| US-5773014-A | MIXTURE OF PLANT EXTRACTS AND ETHYLENEDIAMINETETRAACETIC ACID | BIOETICA, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| US-4889941-A | Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase | FISONS CORPORATION (US) | 1989-12-26 | — | — | US | disclosed |
| EP-0288077-A2 | Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase | PENNWALT CORPORATION (US) | 1988-10-26 | — | — | EP | disclosed |
| US-4668805-A | HYPOTENSIVE AGENTS | PENNWALT CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |