Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.53 |
| ▸ | AXL | P30530 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387155 | 0.83 | MAOA (0.75) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL29520747 | 0.83 | MAOA (0.75) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL251095 | 0.83 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL30500254 | 0.83 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL29403794 | 0.83 | MAOA (0.83) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL17264896 | 0.80 | MAOA (0.71) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL2445085 | 0.80 | MAOA (0.71) | MAOAMAP4K4MEN1PSIP1AXL | |
| SCHEMBL13447707 | 0.80 | MAOA (0.71) | MAOAMAP4K4MEN1PSIP1AXL | |
| Water SCHEMBL2444002 | 0.80 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL | |
| Ammonia Solution, Strong SCHEMBL21296174 | 0.80 | MAOA (0.79) | MAOAMAP4K4MEN1PSIP1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |