Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696705 | 0.86 | TSHR (0.47) | ALDH1A1TSHRHSD17B10HTTHPGD | |
| SCHEMBL7697443 | 0.84 | TP53 (0.45) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL7701856 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL7701098 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL7701099 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRKDM4EHTTTP53 | |
| SCHEMBL7696694 | 0.71 | UBE2N (0.42) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL7667933 | 0.68 | ALDH1A1 (0.67) | ALDH1A1TSHRKDM4EHTTHPGD | |
| SCHEMBL7663107 | 0.67 | ALDH1A1 (0.47) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL7696800 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRKDM4EHSD17B10HTT | |
| SCHEMBL7696766 | 0.66 | ALDH1A1 (0.40) | ALDH1A1TSHRKDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |