Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696705 | 0.87 | TSHR (0.47) | TP53MAPTALDH1A1TSHRHTT | |
| SCHEMBL7703231 | 0.84 | ALDH1A1 (0.39) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7701856 | 0.82 | ALDH1A1 (0.46) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7696676 | 0.77 | TP53 (0.43) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7696678 | 0.76 | ALDH1A1 (0.60) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7696694 | 0.74 | UBE2N (0.42) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7667933 | 0.71 | ALDH1A1 (0.67) | MAPTALDH1A1TSHRKDM4EHTT | |
| SCHEMBL7663107 | 0.70 | ALDH1A1 (0.47) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7696800 | 0.70 | ALDH1A1 (0.45) | TP53MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL7700902 | 0.69 | ALDH1A1 (0.44) | TP53MAPTALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |