SCHEMBL7703341

SCHEMBL7703341

CC(c1ccccc1)c1ccc2cc(O)c(C(=O)O)cc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 1/20 0.44
GRIN2D O15399 1/20 0.43
GRIN2A Q12879 1/20 0.43
GRIN2B Q13224 1/20 0.43
GRIN2C Q14957 1/20 0.43
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MPL P40238 1/20 0.40
UGT2B7 P16662 1/20 0.40
TYR P14679 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.40
MITF O75030 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL658651 0.83 KDM4E (0.56) ACMSDKMT2ATDP1KDM4EALDH1A1
SCHEMBL1373696 0.83 KDM4E (0.56) ACMSDKMT2ATDP1KDM4EALDH1A1
SCHEMBL5964731 0.81 KDM4E (0.54) ACMSDKMT2ATDP1KDM4EALDH1A1
SCHEMBL9769790 0.79 GRIN2D (0.47) ACMSDGRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL6403723 0.79 TYR (0.49) ADRA2AADRA2BADRA2CKMT2AUGT2B7
SCHEMBL2349014 0.77 GRIN2D (0.61) ACMSDGRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL6460 0.77 GRIN2D (0.66) ACMSDGRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL29358330 0.77 GRIN2D (0.66) ACMSDGRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL11555248 0.77 LDHA (0.57) KMT2AKDM4EALDH1A1HPGDMEN1
SCHEMBL11020997 0.76 TYR (0.56) ADRA2AADRA2BADRA2CKMT2AUGT2B7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5994016-A MIXTURE OF HYDROPHOBIC TITANIA AND A CHARGE CONTROLLING AGENT RICOH COMPANY, LTD. (JP) 1999-11-30 US claimed
US-4845003-A COMPLEX COMPOUND OF ALUMINUM AND AN AROMATIC HYDROXYCARBOXYLIC ACID ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1989-07-04 US claimed
US-6358304-B1 Ink with flow characteristics UHLICH COLOR COMPANY, INC. 2002-03-19 US disclosed
US-5994016-A MIXTURE OF HYDROPHOBIC TITANIA AND A CHARGE CONTROLLING AGENT RICOH COMPANY, LTD. (JP) 1999-11-30 US disclosed
US-5403690-A Thermoplastic resin, coloring agent, fluorine containing quaternary ammonium or iminium salt compound and aromatic hydroxycarboxylic acid metallic salt RICOH COMPANY, LTD. (JP) 1995-04-04 US disclosed
EP-0280272-B1 A TONER FOR DEVELOPING ELECTROSTATIC LATENT IMAGES AND A METHOD OF PREPARING THE TONER ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-05 EP disclosed
US-4845003-A COMPLEX COMPOUND OF ALUMINUM AND AN AROMATIC HYDROXYCARBOXYLIC ACID ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1989-07-04 US disclosed
EP-0280272-A2 A toner for developing electrostatic latent images and a method of preparing the toner ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1988-08-31 EP disclosed