SCHEMBL9769790

SCHEMBL9769790

CC(c1ccccc1)c1cc(C(C)c2ccccc2)c2cc(O)c(C(=O)O)cc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
TYR P14679 1/20 0.43
MPL P40238 2/20 0.40
KDM4E B2RXH2 5/20 0.38
HSD17B10 Q99714 5/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
USP2 O75604 1/20 0.38
POLB P06746 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
GRM1 Q13255 4/20 0.38
IGFBP3 P17936 1/20 0.37
ALDH1A1 P00352 4/20 0.36
HPGD P15428 4/20 0.36
TDP1 Q9NUW8 3/20 0.36
GRM2 Q14416 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11025144 0.84 TYR (0.53) TYRKDM4EALDH1A1CYP2C9CYP2C19
SCHEMBL7703341 0.79 ACMSD (0.44) GRIN2DGRIN2AGRIN2BGRIN2CTYR
SCHEMBL11759301 0.78 TYR (0.56) GRIN2DGRIN2AGRIN2BGRIN2CTYR
SCHEMBL11758511 0.78 TYR (0.56) GRIN2DGRIN2AGRIN2BGRIN2CTYR
SCHEMBL312340 0.77 TYR (0.46) TYRKDM4EHSD17B10MEN1KMT2A
SCHEMBL8425731 0.76 TYR (0.45) TYRKDM4EHSD17B10MEN1KMT2A
SCHEMBL11759875 0.76 TYR (0.45) TYRKDM4EHSD17B10MEN1KMT2A
SCHEMBL9771279 0.76 TYR (0.45) TYRKDM4EHSD17B10MEN1KMT2A
SCHEMBL9250673 0.76 ALDH1A1 (0.50) GRIN2DGRIN2AGRIN2BGRIN2CTYR
SCHEMBL11759869 0.76 TYR (0.45) TYRKDM4EHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-4134847-A HOMOGENIZING AN AROMATIC CARBOXYLIC ACID-POLYMER-METAL CARBONATE OR OXIDE MELT KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1979-01-16 US disclosed
US-4046941-A PRESSURE SENSITIVE COPYING SANKO CHEMICAL COMPANY LTD. (JA) 1977-09-06 US disclosed