Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 9/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709692 | 0.80 | TYMS (0.51) | TYMSALDH1A1MAPTTHRBALOX15 | |
| SCHEMBL7706407 | 0.79 | MAPT (0.51) | ERN1ALDH1A1LCKGLAMAPT | |
| SCHEMBL10832427 | 0.78 | KMT2A (0.50) | ERN1ALDH1A1LCKGLAMAPT | |
| SCHEMBL7703859 | 0.78 | TYMS (0.49) | TYMSMAPTTHRBALOX15TDP1 | |
| SCHEMBL7709815 | 0.77 | TYMS (0.45) | TYMSALDH1A1MAPTALOX15TDP1 | |
| SCHEMBL30608351 | 0.74 | TYMS (0.61) | TYMSALDH1A1MAPTTHRBALOX15 | |
| SCHEMBL4533766 | 0.74 | TYMS (0.61) | TYMSALDH1A1MAPTTHRBALOX15 | |
| SCHEMBL7709458 | 0.73 | MEN1 (0.57) | TYMSALDH1A1MAPT | |
| SCHEMBL29836499 | 0.71 | TYMS (0.49) | TYMSALDH1A1MAPTTHRBALOX15 | |
| SCHEMBL7709537 | 0.71 | TYMS (0.49) | TYMSERN1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |