Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TYMS | P04818 | 10/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703712 | 0.82 | TYMS (0.44) | MEN1KMT2AMAPTALDH1A1TYMS | |
| SCHEMBL1133994 | 0.82 | TYMS (0.44) | MEN1KMT2AMAPTALDH1A1TYMS | |
| SCHEMBL7709580 | 0.80 | KMT2A (0.68) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7712218 | 0.79 | KMT2A (0.46) | MEN1KMT2AMAPTALDH1A1TYMS | |
| SCHEMBL7709692 | 0.78 | TYMS (0.51) | MEN1KMT2AMAPTALDH1A1TYMS | |
| SCHEMBL11412757 | 0.77 | TYMS (0.46) | MEN1KMT2AMAPTALDH1A1TYMS | |
| SCHEMBL7703859 | 0.75 | TYMS (0.49) | MEN1KMT2AMAPTTYMSHPGD | |
| SCHEMBL9362534 | 0.74 | TYMS (0.41) | MEN1KMT2AMAPTALDH1A1TYMS | |
| SCHEMBL4084412 | 0.73 | TYMS (0.44) | MEN1KMT2AALDH1A1TYMSLMNA | |
| SCHEMBL29665023 | 0.73 | TYMS (0.44) | MEN1KMT2AALDH1A1TYMSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362181-B1 | BACTERICIDES; ENZYME INHIBITORS; ANTITUMOR AGENTS | WARNER-LAMBERT COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6177423-B1 | N-(HYDROXY OR PROTECTED HYDROXY)-BENZO(DE)ISOQUINOLINE-1,3-DIONE DERIVATIVES; BACTERIAL DNA GYRASE AND DNA TOPOISOMERASE INHIBITORS USEFUL FOR ANTIBACTERIAL AGENTS HAVING REDUCED DRUG RESISTANCE AND REDUCED SIDE EFFECTS | WARNER-LAMBERT COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | disclosed |
| US-4210757-A | Novel naphthoylene-perinones disperse dyestuffs | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4207107-A | Novel ortho-quinone diazide photoresist sensitizers | RCA CORPORATION (US) | 1980-06-10 | — | — | US | disclosed |
| US-4067889-A | 2-CYANO-3-AMINO-BENZANTHRONES AS PRECURSORS | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-3970675-A | ANTHRONE-AMIDINE | CIBA-GEIGY CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |