SCHEMBL7703374

SCHEMBL7703374

COc1cccc(N2C(=O)CC(=O)NC2=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 1.00
MEN1 O00255 8/20 0.72
KMT2A Q03164 8/20 0.72
HSD17B10 Q99714 3/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
RAB9A P51151 1/20 0.70
L3MBTL1 Q9Y468 3/20 0.68
MGLL Q99685 1/20 0.55
POLB P06746 1/20 0.50
ALOX5 P09917 1/20 0.49
ADRB1 P08588 1/20 0.49
CYP1A2 P05177 2/20 0.48
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
GAA P10253 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25228060 0.88 MAPT (0.79) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL7701199 0.83 MEN1 (1.00) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL9802946 0.81 MAPT (1.00) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL8115519 0.81 MAPT (0.68) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL11876925 0.80 MEN1 (1.00) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL5120438 0.79 MEN1 (0.71) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL25633552 0.78 MEN1 (1.00) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL11083258 0.78 MAPT (0.64) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL30458052 0.78 MEN1 (1.00) MAPTMEN1KMT2AHSD17B10SMN1; SMN2
SCHEMBL5665907 0.77 MEN1 (0.68) MAPTMEN1KMT2AHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6342339-B2 AQUEOUS DISPERSION EASTMAN KODAK COMPANY 2002-01-29 US disclosed
US-20010038979-A1 Aggregated dyes for radiation-sensitive elements HELBER MARGARET JONES (US) 2001-11-08 US disclosed
US-20010038978-A1 Aggregated dyes for radiation-sensitive elements HELBER MARGARET JONES (US) 2001-11-08 US disclosed
US-6306567-B1 WITH METHINE CONTAINING PYRIMIDINE DYE EASTMAN KODAK COMPANY 2001-10-23 US disclosed
US-6300046-B1 PHOTOGRAPHIC FILMS FOR MULTILAYER LIGHT SENSETIVE ELEMENTS WITH PYRIMIDINE CYANINE DYES EASTMAN KODAK COMPANY 2001-10-09 US disclosed
US-6291149-B1 PHOTOGRAPHIC FILMS FOR LIGHT SENSITIVE ELEMENTS AND LIGHT INSENSITIVE ELEMENTS EASTMAN KODAK COMPANY 2001-09-18 US disclosed
EP-0778493-B1 Aggregated dyes for radiation-sensitive elements EASTMAN KODAK CO (US) 2001-08-01 EP disclosed
US-6183944-B1 SPECTRAL ABSORBANCE MAXIMUM BATHOCHROMICALLY SHIFTED AND EXHIBITS AN UNUSUALLY HIGH EXTINCTION COEFFICIENT AND AN EXCEPTIONALLY NARROW HALFBANDWIDTH RELATIVE TO ITS NON-AGGREGATED SOLUTION ABSORBANCE SPECTRUM; PHOTOGRAPHY EASTMAN KODAK COMPANY 2001-02-06 US disclosed
EP-0778493-A1 Aggregated dyes for radiation-sensitive elements EASTMAN KODAK COMPANY (US) 1997-06-11 EP disclosed