Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724227 | 0.81 | GAA (0.73) | MAPTMGLLGAAADRB1HSD17B10 | |
| SCHEMBL11842431 | 0.80 | L3MBTL1 (0.64) | MAPTMGLLGAAADRB1HSD17B10 | |
| SCHEMBL7703374 | 0.78 | MAPT (1.00) | MAPTMGLLGAAADRB1CYP1A2 | |
| SCHEMBL11076904 | 0.78 | KMT2A (0.61) | MAPTMGLLGAAADRB1CYP1A2 | |
| SCHEMBL30357056 | 0.77 | MAPT (0.52) | MAPTMGLLGAAADRB1CYP1A2 | |
| SCHEMBL28970967 | 0.77 | MAPT (0.52) | MAPTMGLLGAAADRB1CYP1A2 | |
| SCHEMBL3868423 | 0.77 | AR (0.48) | MAPTMGLLHSD17B10CASP1CASP7 | |
| SCHEMBL27532849 | 0.77 | MGLL (0.62) | MAPTMGLLGAACYP1A2HSD17B10 | |
| SCHEMBL5182226 | 0.77 | FAAH (0.56) | MAPTMGLLGAAHSD17B10KMT2A | |
| SCHEMBL8115519 | 0.77 | MAPT (0.68) | MAPTMGLLGAAADRB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109925-A1 | Microbicidal imidazolidine-2,4-dione derivatives | CIBA-GEIGY AG (CH) | 1984-05-30 | — | — | EP | disclosed |