SCHEMBL7703409

SCHEMBL7703409

Cc1ccc(SC(=O)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.48
HPGD P15428 5/20 0.48
ALDH1A1 P00352 5/20 0.44
LMNA P02545 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NR1I2 O75469 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
DNMT1 P26358 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462546 0.78 MAPT (0.56) MAPTHPGDALDH1A1LMNAKMT2A
SCHEMBL7518002 0.78 MAPT (0.50) MAPTHPGDALDH1A1LMNAKMT2A
Hydrochloric Acid SCHEMBL11852203 0.76 MAPT (0.48) MAPTHPGDALDH1A1LMNAKMT2A
SCHEMBL7162336 0.76 MAPT (0.43) MAPTHPGDALDH1A1LMNAKMT2A
SCHEMBL10427648 0.76 MAPT (0.48) MAPTHPGDALDH1A1LMNAKMT2A
SCHEMBL5847804 0.76 CES2 (0.42) MAPTHPGDALDH1A1KMT2AHTT
SCHEMBL10783553 0.76 SMN1; SMN2 (0.45) MAPTALDH1A1KMT2ACES2CES1
SCHEMBL11568437 0.76 HPGD (0.51) MAPTHPGDALDH1A1LMNACES2
SCHEMBL10779121 0.76 ALDH1A1 (0.50) MAPTHPGDALDH1A1LMNAKMT2A
SCHEMBL979444 0.75 FFAR1 (0.44) MAPTHPGDALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4551545-A Process of preparing alkyl cis chrysanthemates ROUSSEL UCLAF (FR) 1985-11-05 US claimed
JP-5025090-A None JP disclosed
US-20250059227-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME RIKEN GENESIS CO., LTD. (JP) 2025-02-20 US disclosed
EP-4458836-A1 NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME Riken Genesis Co., Ltd. (JP) 2024-11-06 EP disclosed
WO-2023127857-A1 NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME 株式会社理研ジェネシス 2023-07-06 WO disclosed
US-6350863-B1 RIBOFURANOSE SUBSTITUTED WITH 2 BENZYLAMINES FORMED BY REACTION OF 1-BROMO-3,4-DIAMINOBENZENE AND 1,2-BIS/CHLORO DIMETHYSILYLETHANE CANON KABUSHIKI KAISHA (JP) 2002-02-26 US disclosed
US-6011143-A Artificial nucleic acids and a method of making CANON KABUSHIKI KAISHA (JP) 2000-01-04 US disclosed
JP-H0525090-A INTERMEDIATE COMPOUND FOR PRODUCING ALKYL CIS-CHRYSANTHEMATE ROUSSEL UCLAF 1993-02-02 JP disclosed
EP-0280927-B1 MONO- AND DIEPOXIDE DERIVATIVES OF DELTA 22-LL-F28249 COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1992-06-10 EP disclosed
US-4946852-A ANTICHOLESTEROL AGENT HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-07 US disclosed
US-4695644-A Process for producing phenyl chlorothioformates TOYO SODA MANUFACTURING CO., LTD. (JP) 1987-09-22 US disclosed
US-4677218-A INSECTICIDES ROUSSEL UCLAF (FR) 1987-06-30 US disclosed
US-4551545-A Process of preparing alkyl cis chrysanthemates ROUSSEL UCLAF (FR) 1985-11-05 US disclosed
US-4550160-A Processes for the interconversion of C-076 compounds MERCK & CO., INC. (US) 1985-10-29 US disclosed
US-4328335-A PARASITICIDES, CULTURE PRODUCT OF STREPTOMYCES REACTED WITH A THIOCARBONYL HALIDE MERCK & CO., INC. (US) 1982-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250059227-A1 ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME NSUN3, NSUN2, LUC7L2 MAPT 4381/4885HPGD 4455/4885ALDH1A1 1167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.