Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.49 |
| ▸ | FNTB | P49356 | 9/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703456 | 1.00 | FNTA (0.49) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL7711870 | 0.79 | TBXA2R (0.45) | CYP24A1 | |
| SCHEMBL7711873 | 0.79 | TBXA2R (0.45) | CYP24A1 | |
| SCHEMBL8199503 | 0.78 | CA2 (0.46) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL9461939 | 0.75 | CA2 (0.69) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL1158033 | 0.75 | CA2 (0.69) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL1158031 | 0.75 | CA2 (0.69) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL7703375 | 0.75 | FNTA (0.45) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL8617640 | 0.75 | FNTA (0.45) | FNTAFNTBCA2CA1CA12 | |
| SCHEMBL7703378 | 0.75 | FNTA (0.45) | FNTAFNTBCA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |