Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 14/20 | 0.44 |
| ▸ | FNTB | P49356 | 14/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703460 | 0.78 | FNTA (0.49) | CA2CA1CA12CA9FNTA | |
| SCHEMBL7703456 | 0.78 | FNTA (0.49) | CA2CA1CA12CA9FNTA | |
| SCHEMBL1158033 | 0.76 | CA2 (0.69) | CA2CA1CA12CA9FNTA | |
| SCHEMBL9461939 | 0.76 | CA2 (0.69) | CA2CA1CA12CA9FNTA | |
| SCHEMBL1158031 | 0.76 | CA2 (0.69) | CA2CA1CA12CA9FNTA | |
| SCHEMBL8205624 | 0.75 | CA2 (0.46) | CA2CA1CA12CA9FNTA | |
| Water SCHEMBL28867161 | 0.74 | CA2 (0.67) | CA2CA1CA12CA9FNTA | |
| Lithium SCHEMBL6646645 | 0.74 | CA2 (0.67) | CA2CA1CA12CA9FNTA | |
| SCHEMBL6646636 | 0.74 | CA2 (0.67) | CA2CA1CA12CA9FNTA | |
| SCHEMBL8206395 | 0.71 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |