Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703278 | 1.00 | TBXAS1 (0.43) | TBXAS1CYP19A1CYP11B1CYP11B2CYP24A1 | |
| SCHEMBL7703282 | 1.00 | TBXAS1 (0.43) | TBXAS1CYP19A1CYP11B1CYP11B2CYP24A1 | |
| SCHEMBL7241235 | 0.89 | CYP19A1 (0.46) | TBXAS1CYP19A1CYP11B1CYP11B2CYP24A1 | |
| SCHEMBL7669536 | 0.82 | TBXAS1 (0.56) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7669542 | 0.82 | TBXAS1 (0.56) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7708783 | 0.82 | FNTA (0.49) | — | |
| SCHEMBL7708788 | 0.82 | FNTA (0.49) | — | |
| SCHEMBL8228722 | 0.82 | CYP19A1 (0.45) | TBXAS1CYP19A1 | |
| SCHEMBL7240901 | 0.81 | TBXAS1 (0.55) | TBXAS1CYP19A1 | |
| SCHEMBL7240899 | 0.81 | TBXAS1 (0.55) | TBXAS1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414145-B1 | TREATING CANCER AND NEUROFIBROMATOSIS | ZENECA LIMITED (GB) | 2002-07-02 | — | — | US | disclosed |