Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696748 | 0.85 | L3MBTL1 (0.51) | DRD4DRD2DRD3KDM4EHDAC1 | |
| SCHEMBL7692562 | 0.85 | L3MBTL1 (0.51) | DRD4DRD2DRD3KDM4EHDAC1 | |
| SCHEMBL7702285 | 0.85 | L3MBTL1 (0.51) | DRD4DRD2DRD3KDM4EHDAC1 | |
| SCHEMBL7693885 | 0.85 | L3MBTL1 (0.51) | DRD4DRD2DRD3KDM4EHDAC1 | |
| SCHEMBL7210942 | 0.83 | NR5A1 (0.51) | TP53 | |
| SCHEMBL9699146 | 0.83 | NR5A1 (0.51) | TP53 | |
| SCHEMBL4748690 | 0.83 | NR5A1 (0.51) | TP53 | |
| SCHEMBL4749149 | 0.83 | NR5A1 (0.51) | TP53 | |
| SCHEMBL4745433 | 0.83 | NR5A1 (0.51) | TP53 | |
| SCHEMBL4748293 | 0.83 | NR5A1 (0.51) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |